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Table 16-9

Microvascular bleeding with hypofibrinogenemia
  • DIC with fibrinogen <80–100 mg/dL
  • Hemorrhage or massive transfusion with fibrinogen <100–150 mg/dL
Prophylaxis in patients with hemophilia A and vWD (if specific factor concentrates are unavailable or ineffective because of inhibitors)
Prophylaxis for patients with congenital dysfibrinogenemias

DIC = disseminated intravascular coagulation; vWD = von Willebrand disease.