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Table 15-3

AgentBolus (IV)Continuous Infusionα1α2β1β2Dopamine1Dopamine2
Phenylephrine50–100 µg0.15 µg/kg/min+++++?+/–00
(10 mg in 250 mL, 40 µg/mL)
Norepinephrine0.1 µg/kg/min+++++++++++++00
(4 mL in 250 mL, 16 µg/mL)
Epinephrine2–8 µg* 0.015 µg/kg/min+++++++++++++++0
0.3– 0.5 µg† (1 mL in 250 mL, 4 µg/mL)
Ephedrine5–10 mg++?+++++0
Dopamine2–10 µg/kg/min+ to?+++++++++?
(200 mg in 250 mL, 800 µg/mL++++
Dobutamine2–30 µg/kg/min0 to +?++++++0
(250 mg in 250 mL, 1,000 µg/mL)
Isoproterenol4 µg0.015 µg/kg/min (0.15 µg/kg/min to desired effect for third-degree heart block)00++++++++++0
1 mg in 250 mL, 4 µg/mL

*Dose to treat hypotension.

†Dose to treat cardiac arrest.

IV = intravenous.