| Verapamil | Nifedipine | Diltiazem | |
|---|---|---|---|
| Dose | |||
| IV (µg/kg) | 75–150 | 5–15 | 75–150 |
| PO (mg every 8 hr) | 80–160 | 10–20 | 60–90 |
| Negative inotropy | + | 0 | 0/+ |
| Negative chronotropy | + | 0 | 0/+ |
| Negative dromotropy | ++++ | 0 | +++ |
| Coronary artery vasodilation | ++ | ++++ | +++ |
| Systemic vasodilation | ++ | ++++ | ++ |
| Bronchodilation | 0/+ | 0/+ | |
| Elimination half-time (hr) | 2–7 | 4–5 | 4 |
| Route of elimination | Renal | Renal | Hepatic |
IV = intravenous; PO = per os.