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Table

Carboxyhemoglobin Levels*Comments (Symptoms/Signs)
<1%Healthy nonsmokers (None)
2%Level found in urban exercisers
2–4%May cause subtle effects in some persons with coronary disease
3–15%Typical levels found in light to heavy smokers
5%Typical levels found in people who smoke one pack of cigarettes a day

*Carboxyhemoglobin levels above 10–25% are typically considered potentially significant, that is, capable of causing long-lasting neurological consequences. However, brain injury may occur at higher or lower levels. The significance of carboxyhemoglobin levels in the blood can only be determined by the clinical setting/exposure and physical examination.