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Definition

coreceptor

(kōrē-sep'tŏr )

[com- + receptor]

A structure on a cell membrane that enhances the action of the cell receptor.

CCR5 c.A cell surface receptor found on macrophages that facilitates entry of HIV-1 into these cells. Chemokines released by T cells attempt to compete with HIV by blocking the receptor to prevent infection.

CXCR4 c.A cell surface receptor found on T cells that facilitates entry of HIV-1 into these cells. SYN: fusin.