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Definition

Bence Jones protein

(bens jōnz )

[Henry Bence Jones, Brit. physician, 1814–1873]

The light chain portion of immunoglobulin molecules that may be deposited in the renal tubules and excreted in the urine of patients with multiple myeloma, Waldenstrom macroglobulinemia, or some lymphomas. It may contribute to chronic kidney disease in affected patients.