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Definition

Stevens-Johnson syndrome

(stē'vĕnz-jon'sŏn )

[Albert M. Stevens, 1884–1945, Frank C. Johnson, 1894–1934, U.S. pediatricians]

A systemic skin disease, possibly identical to toxic epidermal necrolysis, that produces fevers and lesions of the oral, conjunctival, and vaginal mucous membranes. It is marked by a cutaneous rash that is often widespread and severe. Skin loss may lead to dehydration, infection, or death.

SEE: erythema multiforme; toxic epidermal necrolysis; illus.; erythema multiforme.

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