| Antigen Name or Designation | Abbreviation | The Tumor It Detects or Monitors |
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| Alpha-fetoprotein | AFP | Nonseminomatous germ cell tumor | | CA 15–3 | | Breast cancer | | CA 19–9 | | Pancreatic cancer | | CA 27–29 | | Breast cancer | | CA 50 | | Gastrointestinal tract tumors | | CA 125 | | Ovarian/peritoneal cancer | | Calcitonin | | Medullary cancer of the thyroid gland | | Carcinoembryonic antigen | CEA | Gastrointestinal tract tumors and tumors of solid internal organs | | CD 20 | | Non-Hodgkin lymphoma | | Cytokeratin fragment 21-1 | | Lung cancer | | Estrogen receptor | ER | Breast cancer | | HE4 | | Ovarian cancer | | Human chorionic gonadotropin | HCG | Nonseminomatous germ cell tumors; choriocarcinoma | | Human epidermal growth factor receptor 2 | HER2/neu | Breast and gastric cancers; adenocarcinoma of the gastroesophageal junction | | Immunoglobulins | | Multiple myeloma; Waldenstrom macroglobulinemia | | Microglobulin-beta 2 subunit | b2–M | Multiple myeloma | | Neuron-specific enolase | NSE | Broad variety of cancers, including small-cell carcinoma of lung | | NY-BR-40 and others | | Breast cancer | | Prostate specific antigen | PSA | Prostate cancer | | Thyroglobulin | | Thyroid cancer | | Urinary tumor associated antigen | UTAA | Melanoma |
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Note: several antigens on this list also detect benign diseases and conditions.