[Fredrick Pei Li, Chinese-born U.S. epidemiologist, b. 1940; Joseph F. Fraumeni, Jr., U.S. epidemiologist, b. 1933]

An inherited condition in which individuals develop multiple primary tumors, including breast cancer, osteosarcoma, chondrosarcoma, soft tissue sarcoma, brain tumors, adrenal cortex tumors, etc. Mutations of the p53 gene on chromosome 17 are responsible for this disease.