| Ectoderm | Mesoderm | Endoderm |
|---|
| Nervous tissue | Bone, cartilage, and other connective tissues | Epithelium of respiratory tract except nose; digestive tract except mouth and anal canal; bladder except trigone |
| Sense organs | Male and female reproductive tracts | Proximal portion of male urethra |
| Epidermis, nails, and hair follicles | Heart, blood vessels, and lymphatics | Female urethra |
| Epithelium of external and internal ear, nasal cavity and sinuses, mouth, anal canal | Kidneys, ureters, trigone of bladder | Liver |
| Distal portion of male urethra | Pleura, peritoneum, and pericardium | Pancreas |
| Skeletal muscle | |