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Definition

slow-reacting substance of anaphylaxis

ABBR: SRS-A

Former name given to leukotrienes C4, D4, and E4, arachidonic acid metabolites that contribute to the pathophysiology of asthma, causing prolonged bronchoconstriction, increased vascular permeability, increased bronchial mucous secretion, and vasoconstriction.

SYN: leukotriene.

SEE: arachidonic acid; asthma.