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Evidence summaries

Enteral Nutrition Vs. Steroid Therapy for Induction of Remission in Crohn's Disease

Steroids are more effective than enteral nutrition for induction of remission in Crohn's disease. Level of evidence: "A"

A Cochrane review [Abstract] 1 included 8 studies comparing enteral nutrition to steroid therapy. Meta-analysis of 6 trials (n=352) yielded a pooled OR of 0.33 favouring steroid therapy (95% CI 0.21 to 0.53).

    References

    • Zachos M, Tondeur M, Griffiths AM. Enteral nutritional therapy for induction of remission in Crohn's disease. Cochrane Database Syst Rev 2007 Jan 24;(1):CD000542. [PubMed]

Primary/Secondary Keywords