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Evidence summaries

Vaccines for Preventing Plaque

There is no data from controlled trials evaluating the effectiveness of plaque vaccines. Level of evidence: "D"

According to a Cochrane review [Abstract] 1 there are no controlled trials. According to circumstantial evidence from observational studies killed types may be more effective and have fewer adverse effects than attenuated types of vaccine.

    References

    • Jefferson T, Demicheli V, Pratt M. Vaccines for preventing plague. Cochrane Database Syst Rev. 1998;(1):CD000976 [Review content assessed as up-to-date: 22 February 2009].

Primary/Secondary Keywords