In about 30-40% of cases, premature labour begins after preterm premature rupture of membranes.
After rupture of membranes, the mother should be monitored at a hospital, and broad-spectrum antimicrobials should be given for at least 3 days Antibiotics for Preterm Rupture of Membranes.
Further treatment depends on the clinical status.
After preterm premature rupture of membranes, pregnancy may continue for several days/weeks if no signs of infection or other abnormality develop.
Atosiban (oxytocin receptor antagonist) Oxytocin Receptor Antagonists for Inhibiting Preterm Labour instead of nifedipine for the time of transportation, for example. Atosiban has fewer maternal adverse effects but is no more effective than calcium channel blockers in prolonging pregnancy.