Criteria |
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Clinical criteria |
1. Acute cutaneous lupus |
2. Chronic cutaneous lupus |
3. Alopecia (nonscarring) |
4. Oral or nasal ulcers |
5. Synovitis involving two or more joints |
6. Serositis (pleuritis or pericarditis) |
7. Nephritis (proteinuria > 500 mg/24 h or red blood cell casts) |
8. Neurological findings (seizures, psychosis, mononeuritis multiplex, myelitis, peripheral or cranial neuropathy, or acute confusional state) |
9. Haemolytic anaemia |
10. Leucopenia (< 4 × 10 9 /l) at least once or lymphopenia (< 1 × 109 /l) at least once |
11. Thrombocytopenia (< 100 × 109 /l) at least once |
Immunological criteria |
12. Anti-dsDNA antibodies |
13. Anti-Sm antibodies |
14. Antiphospholipid antibodies (false-positive RPR, lupus anticoagulant, anticardiolipin [medium or high titer] or anti-beta-2-glycoprotein I) |
15.Low complement (C3, C4 or CH50) |
16. Direct Coombs test in the absence of hemolytic anemia |
17. ANA |
The patient is classified as having SLE if
Source: Petri M, Orbai AM, Alarcón GS ym. Derivation and validation of the Systemic Lupus International Collaborating Clinics classification criteria for systemic lupus erythematosus. Arthritis Rheum 2012;64(8):2677-86. |
Treatment Hydroxychloroquine in the Treatment of Systemic Lupus Erythematosus, Dehydroepiandrosterone (Dhea) for Systemic Lupus Erythematosus (Sle), Treatment of Lupus Nephritis, Drugs for Discoid Lupus Erythematosus, Cyclophosphamide Versus Methylprednisolone for Treating Neuropsychiatric Involvement in Sle, Belimumab for Systemic Lupus Erythematosus
Follow-up
Antiphospholipid antibodies
SLE and pregnancy Prevention of Recurrent Miscarriage for Women with Antiphospholipid Antibody or Lupus Anticoagulant, Oral Contraceptives in Women with Systemic Lupus Erythematosus
References
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Primary/Secondary Keywords