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Gfr Calculator

The calculator estimates the glomerular filtration rate (GFR) using the CKD-EPI equation 2. The equation is not applicable to persons under 18 years of age.

Calculator

GFR values over 60 ml/min/1.73 m2 without other signs suggestive of a renal disease (persistent proteinuria or haematuria, microalbuminuria in a patient with diabetes, structural renal defect) require no further investigations or follow-up.

The CKD-EPI is not suitable for the diagnostics of acute renal failure, as is the case with all other calculations that are based on creatinine concentration (the change in creatinine concentration is too slow).

Severity grades of renal failure

Renal functionGFR ml/min/1.73 m2
Normal renal function>90
Mild renal failure (insignificant if there are no other signs of renal disease)60-89
Moderate renal failure30-59
Severe renal failure15-29
End-stage renal failure; dialysis patient<15

Check drug dosage from relevant databases. Notice that the severity grades of renal failure may be defined differently in some databases compared with this calculator.

Calculation of glomerular filtration rate using the CKD-EPI (2021) formula

eGFR (ml/min/1.73 m2) = 142 x min(Scr/κ, 1)α x max(Scr/κ, 1)-1.200 x 0.9938Age x 1.012 [if female]

where:

Scr = standardised plasma or serum creatinine (mg/dl)

κ= 0.7 (female) or 0.9 (male)

α= -0.241 (female) or -0.302 (male)

min(Scr/κ, 1) is the minimum of Scr/κ or 1.0

max(Scr/κ, 1) is the maximum of Scr/κ or 1.0

Age is expressed in full years. It must be at least 18 years.

    References

    • Delgado C, Baweja M, Burrows NR, et al. Reassessing the Inclusion of Race in Diagnosing Kidney Diseases: An Interim Report From the NKF-ASN Task Force. Am J Kidney Dis 2021;78(1):103-115 [PubMed]
    • Inker LA, Eneanya ND, Coresh J, et al. New Creatinine- and Cystatin C-Based Equations to Estimate GFR without Race. N Engl J Med 2021;385(19):1737-1749 [PubMed]
    • Kramer HJ, Jaar BG, Choi MJ, et al. An Endorsement of the Removal of Race From GFR Estimation Equations: A Position Statement From the National Kidney Foundation Kidney Disease Outcomes Quality Initiative. Am J Kidney Dis 2022;80(6):691-696 [PubMed]

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