An infant with bronchiolitis and unable to eat my him/herself or requires supplemental oxygen.
Bronchiolitis in a small infant is associated with apnoea tendency, and the symptoms may progress for 5-6 days after their onset.
Suspected pertussis (whooping cough) in an infant (paroxysmal coughing in a small unimmunized infant).
Assess breathing difficulty by observing the patient's general appearance and work of breathing
Check oxygen saturation, pulse rate, respiratory rate and use of accessory respiratory muscles.
Perform auscultation
Inspiratory stridor is associated with obstruction of the larynx and trachea (laryngitis, epiglottitis, tracheitis),
The wheezing heard in patients with expiratory difficulty may be polyphonic (various frequencies may be heard), which is due to obstruction of several bronchi of different sizes (bronchiolitis, obstructive bronchitis, asthma).
Monophonic expiratory wheezing suggests obstruction of a single airway (foreign body, mucous plug)
Refer the child immediately to hospital care. Ensure adequate oxygenation during transport.
Hib vaccination, which is part of the Finnish national vaccination programme, has reduced the incidence of epiglottitis in children born in Finland to virtually non-existent (1-2 cases per year). Check whether the child has been immunized.
In Finland, expiratory difficulty triggered by an acute viral infection usually in a child aged 12 to 36 months is called obstructive bronchitis (ICD 10: J20.5-J20.9).
The border between obstructive bronchitis, bronchiolitis and childhood asthma is indistinct.
The diagnosis is not difficult: there is a coughing child with rapid and noisy expiration.
On auscultation of the lungs, the expirium is typically prolonged and wheezing can usually be heard. Due to the constriction of bronchi of various sizes, wheezing may be polyphonic, i.e. wheezing of various frequencies may be heard.
However, wheezing is not always heard; auscultation findings may consist only of coarse rales associated with the presence of mucus, predominantly in expiration.
In severe obstruction, auscultation findings may even be interpreted as normal or reduced because of shallow breathing. However, the respiratory rate is nearly invariably increased. It is essential to assess the work of breathing comprehensively by inspection and auscultation.
PEF can usually be successfully measured even in a child of about 6 years, and it should be done also in emergency cases.
Mild obstruction does not always cause visible breathing difficulty but only prolonged expiration or mucus-related rales.
The disease may be interpreted as "incipient bronchitis", and the child may receive a course of antimicrobials, when he/she would actually need a bronchodilator.
It is important to identify those children who are prone to develop symptoms in association with viral infections.
Expiratory difficulty observed by a physician repeatedly (more than 3 times per year) or frequently (2 attacks within 6 weeks) in association with viral infections in a child below school age is an indication for referral for assessment by a paediatrician in specialized care, where the risk factors for asthma are assessed and the start and further follow-up of anti-inflammatory medication planned.
Bronchiolitis denotes the first episode of expiratory breathing difficulty in an infant less than one year of age. RS virus is the most common causative agent Ehttp://www.dynamed.com/condition/bronchiolitis#CAUSES. Viruses such as rhino- and metapneumovirus can also cause a similar clinical picture.
Bronchiolitis is an infection of the most peripheral bronchi (bronchioles) and, as the virus also occurs in the surrounding lung tissue, the disease shows features of viral pneumonia. There may be copious mucus.
A typical patient with bronchiolitis is a small infant with respiratory difficulty; on auscultation, crepitation/crackles and possibly slight expiratory wheezing can be heard. Feeding often becomes more difficult and the child gets easily exhausted. The auscultatory finding may be normal. Increased respiratory rate (> 50/min.) is a significant symptom.
Patients below the age of 3 months should usually be referred for follow-up at hospital because of the risk of apnoea and respiratory insufficiency. High-risk patients include the youngest infants, premature babies and those with a cardiac disorder Ehttp://www.dynamed.com/condition/bronchiolitis#MISC8.
Treatment is symptomatic. In the hospital it consists of monitoring the patient's general condition and taking care of adequate oxygenation, nutrition and clearing of mucus. Warmed and humidified oxygen-air mixture may be administered at a high rate (high flow mask), which may decrease the need for intubation Ehttp://www.dynamed.com/condition/bronchiolitis#MISC8.
Inhaled salbutamol, racemic adrenaline, hypertonic saline or glucocorticoids do not, according to studies, alleviate the symptoms or decrease the need for hospital treatment of infants with bronchiolitis Ehttp://www.dynamed.com/condition/bronchiolitis#MISC8.
Mucus cough continuing for several weeks (suspicion of bacterial bronchitis) requires differential diagnostic evaluation (asthma, tuberculosis, ciliary function disturbance, cystic fibrosis).
In school-aged children, sinusitis may also cause mucus cough.
Whooping cough should be suspected particularly in small infants with paroxysmal cough. These patients should be assessed by a paediatrician and followed up at a hospital due to the risk of apnoea, even if they would seem to be well between bouts of coughing.
National Asthma Education and Prevention Program.. Expert Panel Report 3 (EPR-3): Guidelines for the Diagnosis and Management of Asthma-Summary Report 2007. J Allergy Clin Immunol 2007;120(5 Suppl):S94-138. [PubMed]http://www.nhlbi.nih.gov/files/docs/guidelines/asthsumm.pdf
Meissner HC. Viral Bronchiolitis in Children. N Engl J Med 2016;374(1):62-72. [PubMed]