Upper abdominal pain that radiates to the back with possibly associated nausea and vomiting; weight loss, jaundice.
The pain is caused by increased ductal pressure and by neuritis.
Within approx. 8 years 50% of the patients develop endocrine and exocrine pacreatic insufficiency manifested as steatorrhoea, weight loss and diabetes Pancreatic Insufficiency.
Diagnosis
Examinations in primary care
Plasma/urine amylase, urine trypsinogen-2, blood leucocyte count and CRP may be increased during the pain attacks.
Plasma concentrations of alkaline phosphatase and bilirubin are increased in biliary obstruction.
Fasting blood glucose should be determined for detection of diabetes.