A Cochrane review [Abstract] 1 included 17 RCTs enrolling 988 overweight or obese adults with chronic kidney disease (CKD). Weight loss interventions showed weight reduction compared with usual care or control (MD -3.69 kg, 95% CI -5.82 to -1.57; follow-up: 5 weeks to 12 months; 6 trials, n=180). However, there were uncertain effects on body mass index, waist circumference, proteinuria, or blood pressure. Death, cardiovascular events, successful kidney transplantation, nutritional status, cost effectiveness and economic analysis were not measured.
Evidence of certainty is downgraded by study quality, imprecision, indirectness, and heterogeneity.
Date of latest search: 2021-05-24
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