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Acute Bronchitis
Essentials
- The essential symptoms of acute bronchitis are cough and expectoration of sputum that have lasted less than 3 weeks. In addition, there are usually other symptoms of respiratory tract infection (rhinitis, sore throat, hoarseness).
 - Acute bronchitis is usually a viral infection that does not require antimicrobial therapy.
 - The most important issue in the diagnostics is to exclude pneumonia.
 
Aetiology
- The causative pathogens vary according to the epidemiological situation. The most common causative agents include coronaviruses, rhinoviruses, respiratory syncytial (RS) viruses, adenoviruses, parainfluenza and influenza viruses.
 - An aetiological diagnosis cannot be made based on symptoms and clinical findings.
 
Symptoms
- Symptoms of acute bronchitis include:
                    
- cough
 - often purulent sputum
 - dyspnoea
 - wheezing
 - thoracic pain
 - fever rather rarely (10-30% of patients present with fever).
 
                   - The duration of cough is about 2 weeks in most patients.
 - Acute bronchitis is usually associated with an infection in the upper respiratory tract and therefore the patient simultaneously has rhinitis, sore throat and hoarseness.
 - General symptoms are common: headache and debilitation occur in half of patients, muscle pain in one in four.
 
Diagnosis
- Diagnosis is based on patient history, clinical examination and follow-up of the further course.
 - Microbiological tests are of no benefit, except when influenza is suspected in cases where its drug treatment would be indicated.
 - It is essential to identify the patients in whom pneumonia should be suspected (see Differential diagnosis).
                    
- In a generally healthy person without significant general symptoms (heart rate < 100/min, respiratory rate < 20/min, body temperature < 38°C) and without pneumonic rales on auscultation or dullness to percussion, the probability of pneumonia is very small.
 
                   
Differential diagnosis
- The most important differential diagnosis to consider is pneumonia Pneumonia. It is significantly less common than bronchitis.
                    
- The differential diagnosis cannot be based on clinical symptoms and laboratory findings alone. Bronchitis and pneumonia are often caused by the same microbes - these diagnoses constitute differences in severity of the same disease.
 - In bronchitis the infection is limited to the mucous membranes of the bronchial tree while pneumonia represents an inflammation of the lung parenchyma, and its symptoms are therefore more severe.
 
                   
Pneumonia
- Pneumonia may be suspected if the patient has the following symptoms:
- increased respiratory rate > 20/min
 - tachycardia (> 100/min)
 - abnormal findings in the respiratory exam
    
- decreased breath sounds
 - dullness to percussion
 - rales
 - vocal resonance over a larger area than normal
 
   - oxygen saturation < 92% in room air.
 
                     - If pneumonia is suspected, plain x-ray of the chest should be performed.
 - Taking a chest x-ray is further recommended in patients
- with impaired general condition
 - with a prolonged or unusual course of the disease
 - with a primary disease, e.g. COPD, bronchiectasis, diabetes, or chronic cardiac, hepatic or renal disease predisposing them to pneumonia
 - with a history of pneumonia within the past year.
 
                     - CRP > 100 mg/l strongly suggests pneumonia. If the CRP is < 20 mg/l and there are no symptoms or signs fitting pneumonia, pneumonia is unlikely.
- In patients with severe symptoms, low CRP concentration does not exclude the possibility of a serious bacterial disease. CRP measurement is not reliable in the differential diagnostics if the symptoms have lasted less than 24 h.
 
                     
Other differential diagnoses
- The possibility of sinusitis Acute Maxillary Sinusitis should be excluded by ultrasound examination or x-ray in patients with persisting symptoms or local signs of sinusitis. Cough is a common symptom also in common cold, asthma and COPD.
 - The following conditions that sometimes resemble bronchitis should be borne in mind:
                    
 
- Supportive care
 - Symptomatic treatment
                    
                  
 - Generally, antimicrobial drugs should not be used for acute bronchitis http://www.dynamed.com/condition/acute-bronchitis#ANTIBIOTICS, because it is usually a viral infection.
                    
                  
 - Because the course of the disease cannot be predicted from the clinical picture or the laboratory findings, regardless of whether or not antimicrobial therapy is performed, a patient with acute bronchitis must be given a new appointment if symptoms persist or become worse.