Information
Editors
Keratoconus (Conical Degeneration of the Cornea)
Essentials
- Keratoconus (conical degeneration or conical bulging of the cornea) is a disease in which the cornea becomes thinner and more fragile.
 - The pressure in the eye makes the thinned cornea bulge conically outward.
 - Keratoconus often begins at the age of 12-20 years and typically progresses for 10-15 years.
 - In most cases, progression will stop before any significant impairment of visual acuity.
 - Keratoconus may also result from laser-assisted refractive surgery (usually LASIK surgery). In that case, it is called corneal ectasia.
 - The patients should be treated and monitored by an ophthalmologist.
 
Prevalence
- 1 in 1 500-2 000 people
 - There are differences between countries; check local epidemiology.
 
Symptoms and findings
- Reduced visual acuity
                    
- Increased astigmatism and myopia
 
                   - Simultaneous perception of several images of a single object
 - Impaired contrast sensitivity (difficulty distinguishing between various shades of black and white)
 - Thinning cornea
 - Visible protrusion of the corneal surface
 
Workup
- Visual acuity
 - Inspection of the eye: is there conical bulging of the cornea visible on lateral inspection (often best detectable if the patient looks down)?
 - Examinations by an ophthalmologist include corneal tomography and biomicroscopy.
 
Treatment
- Corneal cross-linking strengthens the structure of the cornea and prevents it from protruding forward.
 - Hard contact lenses
 - In advanced cases, corneal transplantation may be considered.