| Symptom or sign | Diagnostic clue |
|---|---|
| Calf or ankle oedema Leg Oedema | Deep venous thrombosis Deep Vein Thrombosis Insufficient valves in deep veins (stasis eczema; Venous Insufficiency of the Lower Limbs) Ruptured Baker's cyst (history of a mass in the popliteal fossa; Baker's Cyst) |
| Erythema of the skin | Erysipelas Erysipelas |
| Local pain in the skin | Superficial thrombophlebitis Superficial Venous Thrombophlebitis |
| Intermittent claudication | Lower limb ischaemia Lower Limb Ischaemia (weak or absent pulses; lowered ankle-brachial index on Doppler ultrasonography) Spinal stenosis Lumbar Spinal Stenosis (LSS) |
| Back pain exacerbated by bending forwards | Sciatica Low Back Pain; pain often felt also elsewhere than in the calf |
| Pain felt near the heel | Achilles tendon injury Achilles Tendinopathy and Tendon Rupture |
| Military conscripts or athletes | Stress fracture (local tenderness on the tibia; Stress Fractures) Compartment syndrome Muscle Compartment Syndromes |
| Sudden onset | Muscle injury Muscle Injuries Ruptured Baker's cyst Arterial embolism (coldness, pulselessness, paleness; Lower Limb Ischaemia) |