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Evidence summaries

Laparoscopic Repair for Perforated Peptic Ulcer Disease

The results of laparoscopic surgery for repair of a perforated peptic ulcer appear to be no clinically different from those of open surgery. Level of evidence: "B"

A Cochrane review [Abstract] 1 included 3 studies with a total of 315 subjects. There was no statistically significant differences between laparoscopic and open surgery in the proportion of abdominal septic complications (OR 0.66, 95% CI 0.30 to 1.47), pulmonary complications (OR 0.52, 95% CI 0.08 to 3.55) or actual number of septic abdominal complications (OR 0.60, 95% CI 0.32 to 1.15).

Comment: The quality of evidence was downgraded by sparse data.

    References

    • Sanabria A, Villegas MI, Morales Uribe CH. Laparoscopic repair for perforated peptic ulcer disease. Cochrane Database Syst Rev 2013;(2):CD004778. [PubMed].

Primary/Secondary Keywords