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Evidence summaries

Grass Allergy and Wheat Allergy (Cereal Allergy)

One third of the patients with skin prick test positive grass allergy (wheat) experience immediate effects on exposure. Level of evidence: "C"

Sampson et al. 1 studied patients who were allergic to cereals and grass pollen with skin prick tests. Commercial allergens (Greer Laboratories, NC, USA) were used for the testing. Wheat allergy was suspected in 126 patients; the skin prick test was positive ( 3 mm) in 65 %. Immediate challenge testing was positive in only 32 %, i.e. the majority of the skin prick test reactions for wheat were false positive results. Patients with grass allergy who had reacted negatively to cereals in challenge testing often developed only slightly positive responses to cereals.

References

  • Jones SM, Magnolfi CF, Cooke SK, Sampson HA. Immunologic cross-reactivity among cereal grains and grasses in children with food hypersensitivity. J Allergy Clin Immunol 1995 Sep;96(3):341-51. [PubMed]

Primary/Secondary Keywords