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Evidence summaries

Computer-Assisted Management of Anticoagulant Therapy

Computer-assisted management of anticoagulant therapy improves the quality of anticoagulation and reduces the number of haemorrhages and other adverse events due to the treatment. Level of evidence: "A"

A systematic review 1 including 9 studies with a total of 1 336 subjects was abstracted in DARE.

The quality of anticoagulation was better in intervention group than control (pooled OR 1.29, 95% CI: 1.12 to 1.49). Results on the effect of intervention on clinical outcomes reported 14 major haemorrhages in 700 participants in the intervention group versus 25 among 636 in the control groups

(2.0% versus 3.9%). Combining all major events (death, major haemorrhage and thromboembolic events) a total of 28 (4.4%) clinical events were reported in the intervention group

and 39 (5.6%) in the control group.

References

  • Chatellier G, Colombet I, Degoulet P. An overview of the effect of computer-assisted management of anticoagulant therapy on the quality of anticoagulation. Int J Med Inform 1998 May;49(3):311-20. [PubMed][DARE]

Primary/Secondary Keywords