Pulmonary Embolism - Related Resources

Cochrane reviews

Thrombolytic therapy is probably not effective for pulmonary embolism in haemodynamically stable patients Thrombolytic Therapy in Pulmonary Embolism.
A negative D-dimer is useful in ruling out pulmonary embolism (PE) in patients who do not have a high pre-test probability of of PE D-Dimer Testing and Pulmonary Embolism.

Negative lung scan, spiral computed tomography in combination with ultrasound, or quantitative D-dimer assay are adequate to rule-out PE where the population prevalence is 35% or less. Positive high probability ventilation perfusion lung scan, spiral computed tomography, or ultrasound are adequate to rule-in PE where the population prevalence is 35% or greater Diagnostic Strategies for Pulmonary Embolism.
There appears not to be difference in heparin-associated thrombocytopenia (HAT) between low molecular weight heparin (LMWH) and unfractionated heparin (UFH) in treatment of pulmonary embolism and deep vein thrombosis Risk for Heparin-Induced Thrombocytopenia (HIT) with Either Low-Molecular-Weight Heparin (Lmwh) or Unfractionated Heparin (Ufh).

Kearon C, Akl EA, Ornelas J et al. Antithrombotic Therapy for VTE Disease: CHEST Guideline and Expert Panel Report. Chest 2016;149(2):315-52. [PubMed]
Torbicki A, Perrier A, Konstantinides S, et al; Task Force for the Diagnosis and Management of Acute Pulmonary Embolism of the European Society of Cardiology. Guidelines on the diagnosis and management of acute pulmonary embolism: the Task Force for the Diagnosis and Management of Acute Pulmonary Embolism of the European Society of Cardiology (ESC). Eur Heart J 2008 Sep;29(18):2276-315.Epub 2008 Aug 30 [PubMed].

Agnelli G, Becattini C. Acute pulmonary embolism. N Engl J Med 2010 Jul 15;363(3):266-74. [PubMed]

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