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Evidence summaries

The Effect of Soy Protein Intake on Serum Lipids

Soy protein-containing diet appears to decrease serum cholesterol, LDL cholesterol and triglyceride levels. Level of evidence: "B"

A systematic review 1 including 38 studies was abstracted in DARE. The ingestion of diets containing soy protein (averagely 47 g/day) compared to control regimens was accompanied by a significant reduction in serum concentrations of total cholesterol (9.3%), LDL cholesterol (12.9%) and triglycerides (10.5%). HDL cholesterol increased 2.4% (not statistically significant).

Comment: The review was not well reported, and its quality is therefore difficult to assess.

References

  • Anderson JW, Johnstone BM, Cook-Newell ME. Meta-analysis of the effects of soy protein intake on serum lipids. N Engl J Med 1995 Aug 3;333(5):276-82. [PubMed] [DARE]

Primary/Secondary Keywords