Dronedarone in the Prevention of Atrial Fibrillation - Flowchart
Dronedarone in the Prevention of Atrial Fibrillation - Flowchart Dronedarone in the Prevention of Atrial Fibrillation Dronedarone in the Prevention of Atrial Fibrillation
«Flowchart»

Echocardiography
Liver function tests (ALT)
Creatinine

Echocardiography
Liver function tests (ALT)
Creatinine

Echocardiography
Liver function tests (ALT)
Creatinine



Normal

Normal

Normal

Abnormal

Abnormal

Abnormal


Heart failure
ALT >3 * upper reference limit
eGFR <30 ml/min


Heart failure
ALT >3 * upper reference limit
eGFR <30 ml/min


Heart failure
ALT >3 * upper reference limit
eGFR <30 ml/min


Heart failure
ALT >3 * upper reference limit *
eGFR <30 ml/min <

Dronedarone 400mg twice daily

Dronedarone 400mg twice daily

Dronedarone 400mg twice daily

FOLLOW-UP


History, clinical examination and ECG every 6 months or more frequently
Liver function tests

FOLLOW-UP


History, clinical examination and ECG every 6 months or more frequently
Liver function tests

FOLLOW-UP


History, clinical examination and ECG every 6 months or more frequently
Liver function tests


History, clinical examination and ECG every 6 months or more frequently
Liver function tests

Dronedarone contraindicated

Dronedarone contraindicated

Dronedarone contraindicated

End

End

End


Liver test values increased (ALT 3 *)
Permanent atrial fibrillation

Suspected heart failure or pulmonary dysfunction


Liver test values increased (ALT 3 *)
Permanent atrial fibrillation

Suspected heart failure or pulmonary dysfunction


Liver test values increased (ALT 3 *)
Permanent atrial fibrillation


Liver test values increased (ALT 3 *) *
Permanent atrial fibrillation

Suspected heart failure or pulmonary dysfunction

Yes

Yes

Yes

Yes

Yes

Yes

No

No

No


Echocardiography
Pulmonary function tests


Echocardiography
Pulmonary function tests


Echocardiography
Pulmonary function tests


Echocardiography
Pulmonary function tests

Normal

Normal

Normal

Abnormal

Abnormal

Abnormal