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Evidence summaries

Fumarates for Psoriasis

Fumarate appears to be an effective systemic treatment for psoriasis. Level of evidence: "B"

According to a systematic review 1 oral fumaric acid ester (fumarate) therapy was found to be an effective systemic treatment for psoriasis. Based on the evidence, dimethylfumarate appears to be the principal active component.

Comment: The qualilty of evidence is downgraded by limitations in review methodology.

    References

    • Griffiths CEM, Clark CM, Chalmers RJG,Li Wan Po A, Williams HC.A systematic review of treatments for severe psoriasis. Health Technol Assess 2000;4(40).

Primary/Secondary Keywords