Epilepsy in Children - Related Resources

Cochrane reviews

Education- or counselling-based interventions for children with epilepsy might possibly improve some outcomes relating to epilepsy in children and to the impact that epilepsy can have on parents, although the evidence is insufficient Care Delivery and Self-Management Strategies for Children with Epilepsy
The risk of seizure recurrence appears to be higher with early withdrawal (less than 2 seizure-free years) than with later withdrawal in children Early Versus Late Antiepileptic Drug Withdrawal in Pediatric Epilepsy.
There is insufficient evidence to compare the treatments for infantile spasms Treatment of Infantile Spasms.
Levetiracetam may reduce seizure frequency when used as an add-on treatment for children with drug-resistant partial epilepsy Levetiracetam Add-on for Drug-Resistant Focal Epilepsy in Children.
Sulthiame might possibly be effective for seizure remission in the short term in children with benign epilepsy with centro temporal spikes, although the evidence is insufficient Treatment of Children with Benign Epilepsy with Centro Temporal Spikes.
Vagal nerve stimulation (VNS) as an add-on treatment is an effective and well tolerated for partial seizures in patients with drug-resistant seizures. VNS stimulation using the high stimulation paradigm is better than low stimulation in reducing frequency of seizures .
Carbamazepine may be more effective than phenobarbitone in terms of treatment retention (withdrawals due to lack of efficacy or adverse events or both) Carbamazepine Versus Phenobarbitone Monotherapy for Epilepsy.
Ketogenic diet might possibly be beneficial for seizure reduction in children and adolescents with epilepsy, even though the adverse effects are frequent. However, the evidence is insufficient Ketogenic Diets for Epilepsy in Children.

OtherInternet resources

Lennox-Gastaut syndrome. Orphanet ORPHA2382 http://www.orpha.net/consor/cgi-bin/Disease_Search.php?lng=EN&data_id=885&Disease_Disease_Search_diseaseGroup=lennox&Disease_Disease_Search_diseaseType=Pat&Disease(s) concerned=Lennox-Gastaut-syndrome&title=Lennox-Gastaut-syndrome&search=Disease_Search_Si

Literature

Glauser TA, Cnaan A, Shinnar S, Hirtz DG, Dlugos D, Masur D, Clark PO, Capparelli EV, Adamson PC, Childhood Absence Epilepsy Study Group. Ethosuximide, valproic acid, and lamotrigine in childhood absence epilepsy. N Engl J Med 2010 Mar 4;362(9):790-9. [PubMed]

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Epilepsy in Children - Related Resources

Cochrane reviews

OtherInternet resources

Literature