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Evidence summaries

Surgery for Thumb (Trapeziometacarpal Joint) Osteoarthritis

There is no evidence if any surgery for osteoarthritis at the base of the thumb has benefits compared to no surgery, and it is unclear which type of surgery should be preferred. Level of evidence: "D"

The level of evidence is downgraded by study limitations (several issues) and indirectness of evidence (direct comparisons not available).

A Cochrane review [Abstract] 1 [withdrawn from publication] included 11 studies with a total of 670 subjects. Studies of seven surgical procedures were identified (trapeziectomy, trapeziectomy with interpositional arthroplasty, trapeziectomy with ligament reconstruction, trapeziectomy with ligament reconstruction and tendon interposition [LRTI], Artelon joint resurfacing, arthrodesis, and joint replacement). No studies compared surgery with sham surgery or surgery with non-surgical interventions.

Trapeziectomy with LRTI may not provide additional benefits or result in more adverse events over trapeziectomy alone. Mean pain (three studies, 162 participants) was 26 mm on a 0 to 100 mm VAS (0 is no pain) for trapeziectomy alone, trapeziectomy with LRTI reduced pain by a mean of 2.8 mm (95% CI -9.8 to 4.2) or an absolute reduction of 3% (-10% to 4%). Mean physical function (three studies, 211 participants) was 31.1 points on a 0 to 100 point scale (0 is best physical function, or no disability) with trapeziectomy alone, trapeziectomy with LRTI resulted in sightly lower function scores (SMD 0.1, 95% CI -0.30 to 0.32), an equivalent to a worsening of 0.2 points (95% CI -5.8 to 6.1) on a 0 to 100 point scale (absolute decrease in function 0.03% (-0.83% to 0.88%)). Four studies (328 participants) indicated that the mean number of adverse events was 10 per 100 participants for trapeziectomy alone, and 19 events per 100 participants for trapeziectomy with LRTI (RR 1.89, 95% CI 0.96 to 3.73) or an absolute risk increase of 9% (95% CI 0% to 28%). One study (42 participants) indicated that the mean scapho-metacarpal distance was 2.3 mm for the trapeziectomy alone group, trapeziectomy with LRTI resulted in a mean of 0.1 mm less distance (95% CI -0.81 to 0.61). None of the included trials reported global assessment, quality of life, and revision or re-operation rates.Two small studies (51 participants) indicated that trapeziectomy with LRTI may not improve function or slow joint degeneration, or produce additional adverse events over trapeziectomy and ligament reconstruction.

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    References

    • Wajon A, Vinycomb T, Carr E et al. WITHDRAWN: Surgery for thumb (trapeziometacarpal joint) osteoarthritis. Cochrane Database Syst Rev 2017;4():CD004631. [PubMed].

Primary/Secondary Keywords