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Evidence summaries

General Health Checks in Adults for Reducing Morbidity and Mortality from Disease

General health checks in adults are not effective for reducing morbidity and mortality. Level of evidence: "A"

Summary

A Cochrane review 09009[Abstract] 1 included 17 randomised trials with a total of 251 891 subjects. Trials specifically targeting older people were excluded. Interventions screening for more than one disease/risk factor were included regardless of the type on healthcare provider. Studies that included a lifestyle intervention (advice on diet, smoking and exercise), in addition to screening were accepted, since this is usual in health checks. Risk of bias was generally low for the primary outcomes. Health checks had no effect on total or cancer mortality, or ischaemic heart disease and little or no effect on cardiovascular mortality or fatal and non-fatal ischaemic heart disease (table T1). Health checks did not reduce morbidity, but they did increase the number of people diagnosed with elevated risk factors. There were little or no difference to hospital admission rates, number of physician visits, or disability (low-certainty evidence). Health checks appeared to slightly improve self-reported health, but it was uncertain whether health checks increase or reduce absence from work.

General health checks for reducing morbidity and mortality from disease

OutcomesRelative effect (95% CI)Assumed risk without health checksCorresponding risk with health checks (95% CI)No of participants (studies) Certainty of the evidence
Total mortalityFollow-up: 4-30 yearsRR 1.00 (0.97 to 1.03)68 per 100068 per 1000 (66 to 70)233 298 (11) High
Cancer mortality Follow-up: 4-22 yearsRR 1.01 (0.92 to 1.12)26 per 100026 per 1000 (24 to 29)139 290 (8) High
Cardiovascular mortality Follow-up: 4-30 yearsRR 1.05 (0.94 to 1.16)32 per 100034 per 1000 (30 to 37)170 227 (9) Moderate
Fatal and non-fatal ischaemic heart disease Follow-up: 4-30 yearsRR 0.98 (0.94 to 1.03)66 per 100065 per 1000 (62 to 68)164 881 (4) High
Fatal and non-fatal stroke Follow-up: 4-30 yearsRR 1.05 (0.95 to 1.17)29 per 100030 per 1000 (28 to 34)107 421 (3) Moderate

Clinical comments

Note

Date of latest search: 2019-05-09

    References

    • Krogsbøll LT, Jørgensen KJ, Gøtzsche PC. General health checks in adults for reducing morbidity and mortality from disease. Cochrane Database Syst Rev 2019;(1):CD009009. [PubMed]

Primary/Secondary Keywords