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Evidence summaries

Topical Nasal Steroids for Intermittent and Persistent Allergic Rhinitis in Children

Topical nasal steroids may decrease symptoms in children with allergic rhinitis. Level of evidence: "C"

A Cochrane review [Abstract] 1 included 3 studies with a total of 79 subjects. All three trials, which compared topical nasal steroids against placebo for perennial rhinitis, provided some, albeit limited data, relevant to our primary outcomes; but in two of the trials the data analysis was flawed and in the third trial it was incomprehensible. None of the trials provided data relevant to our secondary outcomes. There were no adverse events reported from any of the interventions.

Comment: The quality of evidence is downgraded by the study quality and heterogeneity.

    References

    • Al Sayyad JJ, Fedorowicz Z, Alhashimi D, Jamal A. Topical nasal steroids for intermittent and persistent allergic rhinitis in children. Cochrane Database Syst Rev 2007 Jan 24;(1):CD003163. [PubMed]

Primary/Secondary Keywords