The quality of evidence is downgraded by imprecise results (few outcome events and wide confidence interval).
A Cochrane review [Abstract] 1 included 4 studies with a total of 2 818 subjects with severe aortic stenosis (AS) and low surgical risk. The benefits and harms of transcatheter aortic valve implantation (TAVI) were compared to surgical aortic valve replacement (SAVR).
Neither in short- or long-term outcomes, there were no significant differences between TAVI and SAVR in all-cause mortality, stroke, or myocardial infarction, although there were very few events. Fewer people had atrial fibrillation, acute kidney injury, and bleeding when they underwent TAVI compared with SAVR. TAVI increased the risk of permanent pacemaker implantation compared with SAVR.
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