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Evidence summaries

Surgical Versus Non-Surgical Treatment for Lumbar Spinal Stenosis

There is insufficient evidence on the effect of surgical versus non-surgical treatment for lumbar spinal stenosis. Surgery is more frequently associated with complications. Level of evidence: "D"

The quality of evidence is downgraded by study limitations (lack of blinding and failure to adhere to the intention-to-treat principle) and imprecise results (few patients).

Summary

A Cochrane review [Abstract] 1 included 5 studies with a total of 643 subjects. The meta-analysis performed on two trials using the Oswestry Disability Index (pain-related disability) to compare direct decompression with or without fusion versus multi-modal non-operative care showed no significant differences at six months (MD -3.66, 95% CI -10.12 to 2.80) and at one year (MD -6.18, 95% CI -15.03 to 2.66). At 24 months, significant differences favoured decompression (MD -4.43, 95% CI -7.91 to -0.96). One small study revealed no difference in pain outcomes between decompression and usual conservative care (bracing and exercise) at three months (RR) 1.38, 95% CI 0.22 to 8.59), four years (RR 7.50, 95% CI 1.00 to 56.48) and 10 years (RR 4.09, 95% CI 0.95 to 17.58). One small study suggested no differences at six weeks in the Oswestry Disability Index for patients treated with minimally invasive mild decompression versus those treated with epidural steroid injections (MD 5.70, 95% CI 0.57 to 10.83; 38 participants). Zurich Claudication Questionnaire (ZCQ) results were better for epidural injection at six weeks (MD -0.60, 95% CI -0.92 to -0.28), and visual analogue scale (VAS) improvements were better in the mild decompression group (MD 2.40, 95% CI 1.92 to 2.88). The results of a single study including 191 participants favoured the interspinous spacer versus usual conservative treatment at six weeks, six months and one year for symptom severity and physical function. All remaining studies reported complications associated with surgery and conservative side effects of treatment: Two studies reported no major complications in the surgical group, and the other study reported complications in 10% and 24% of participants, including spinous process fracture, coronary ischaemia, respiratory distress, haematoma, stroke, risk of reoperation and death due to pulmonary oedema.

Clinical comments

Note

Date of latest search: 2015-02-11

References

  • Zaina F, Tomkins-Lane C, Carragee E et al. Surgical versus non-surgical treatment for lumbar spinal stenosis. Cochrane Database Syst Rev 2016;1():CD010264. [PubMed]

Primary/Secondary Keywords