A topic in Clinical Evidence 1 summarizes the evidence on digoxin in converting atrial fibrillation to sinus rhythm. Three RCTs with a total of 315 people found that digoxin was no more effective than placebo in converting AF to sinus rhythm (0.88 mg intravenously 51% vs 46%, 1.25 mg intravenously 47% vs 40%, oral digoxin 0.6mg, 0.4mg, 0.2mg and 0.2mg at 0, 4, 8, and 14 hours 50% vs 44%.
CE category: Unlikely to be beneficial.
Comment: The quality of evidence is downgraded by sparse data.
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