Restless Legs and Akathisia - Related Resources

Cochrane reviews

The evidence is insufficient to show whether calf muscle stretching can prevent recurrent lower limb muscle cramps Non-Drug Therapies for Lower Limb Muscle Cramps.
Iron therapy is probably not beneficial for the treatment of restless legs syndrome Iron for Restless Legs Syndrome.
Magnesium is probably not effective for older adults experiencing skeletal muscle cramps. The evidence is lacking for treating pregnancy-associated leg cramps with magnesium Magnesium for Skeletal Muscle Cramps.

Trenkwalder C, Benes H, Poewe W, et al; SP790 Study Group. Efficacy of rotigotine for treatment of moderate-to-severe restless legs syndrome: a randomised, double-blind, placebo-controlled trial. Lancet Neurol 2008 Jul;7(7):595-604. [PubMed]
Hening WA. Current guidelines and standards of practice for restless legs syndrome. Am J Med 2007 Jan;120(1 Suppl 1):S22-7. [PubMed]
Ferini-Strambi L. Treatment options for restless legs syndrome. Expert Opin Pharmacother 2009 Mar;10(4):545-54. [PubMed]

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