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Evidence summaries

Primary Stenting Versus Primary Balloon Angioplasty for Treating Acute Myocardial Infarction

Primary stenting and primary balloon angioplasty do not differ in terms of mortality after acute myocardial infarction. Stenting may be associated with a reduced risk of reinfarction and target vessel revascularization. Level of evidence: "A"

A Cochrane review [Abstract] 1 included 9 studies with a total of 4433 subjects. Odds ratios for mortality after stenting compared to balloon angioplasty at 30 days, 6 and 12 months were 1.16 (95% CI 0.78 to 1.73), 1.27 (95% CI 0.89 to 1.83), and 1.06 (95% CI 0.77 to 1.45). At 30 days, 6 and 12 months odds ratios for reinfarction after stenting compared to balloon angioplasty were 0.52 (95% CI 0.31 to 0.87), 0.67 (95% CI 0.45 to 1.00), and 0.67 (95% CI 0.45-0.98) and odds ratio for target vessel revascularization after stenting compared to balloon angioplasty were 0.45 (95%CI 0.34 to 0.60), 0.42 (95% CI 0.35 to 0.51), and 0.47 (95% CI 0.38 to 0.57). The odds ratio for post-interventional bleeding complications after stenting compared to balloon angioplasty was 1.34 (95% CI 0.95 to 1.88; test of heterogeneity p > 0.1).

    References

    • Nordmann AJ, Bucher H, Hengstler P, Harr T, Young J. Primary stenting versus primary balloon angioplasty for treating acute myocardial infarction. Cochrane Database Syst Rev 2005 Apr 18;(2):CD005313. [PubMed]

Primary/Secondary Keywords