Lymphomas - Related Resources

Cochrane reviews

Adding radiotherapy to chemotherapy improves 5-year overall survival and tumour control in patients with newly diagnosed Hodgkin's lymphoma compared to chemotherapy alone. There is no evidence that complete response rate is different between the treatment groups. Chemotherapy Alone Versus Chemotherapy Plus Radiotherapy for Early Stage Hodgkin Lymphoma
Addition of interferon-alpha (IFN) as maintenance therapy for follicular lymphoma after or concomitant with chemotherapy may improve progression-free survival but a net benefit for overall survival is less evident and IFN is associated with significant toxicities Interferon-Alpha for Maintenance of Follicular Lymphoma.
High-dose chemotherapy followed by autologous stem cell transplantation (HDT) is not more effective in improving overall survival in low-risk patients than control therapies (CT) as initial therapy for aggressive Non-Hodgkin lymphoma (NHL). Poor risk patients seem to benefit from HDT, but the evidence is insufficient High-Dose Chemotherapy Followed by Autologous Stem Cell Transplantation (Hdt) as First-Line Therapy in Aggressive Non-Hodgkin's Lymphoma (NHL).
Prophylactic treatment with granulopoiesis-stimulating factor reduces the risk for neutropenia, febrile neutropenia and infections in patients undergoing conventional chemotherapy for malignant lymphoma, but does not improve overall survival or freedom from treatment failure Granulopoiesis-Stimulating Factors to Prevent Adverse Effects in the Treatment of Malignant Lymphoma.

Other evidence summaries

Systemic therapy is effective and palliative in mycosis fungoides and Sezary syndrome Systemic Therapy for Mycosis Fungoides and Sezary Syndrome.

Other Internet resources

Onkologiayhdistys. Lymfoomaryhmän kansainväliset hoitosuositukset http://www.onkologiayhdistys.fi/fin/alaryhmat/lymfoomaryhma/hoitosuositukset/
PDQ Cancer Information Summaries. Adult non-Hodgkin lymphoma treatment http://www.ncbi.nlm.nih.gov/books/NBK66057/.
PDQ Cancer Information Summaries. Adult Hodgkin lymphoma treatment http://www.ncbi.nlm.nih.gov/books/NBK65804/

Literature

Swerdlow SH, Campo E, Harris NL, ym.. (Eds) WHO Classification of tumours of haematopoietic and lymphoid tissues. 4th edition. International Agency for Research on Cancer (IARC), 2008.
Horning SJ. Risk, cure and complications in advanced hodgkin disease. Hematology Am Soc Hematol Educ Program 2007;2007():197-203. [PubMed]
Radford J. Limited-stage disease: optimal use of chemotherapy and radiation treatment. Hematology Am Soc Hematol Educ Program 2008;2008():321-5. [PubMed]
Salles GA. Clinical features, prognosis and treatment of follicular lymphoma. Hematology Am Soc Hematol Educ Program 2007;2007():216-25. [PubMed]
Savage KJ. Prognosis and primary therapy in peripheral T-cell lymphomas. Hematology Am Soc Hematol Educ Program 2008;2008():280-8. [PubMed]
Sweetenham JW. Diffuse large B-cell lymphoma: risk stratification and management of relapsed disease. Hematology Am Soc Hematol Educ Program 2005;():252-9. [PubMed]
Swerdlow SH, Campo E, Harris NL, et al. WHO Classification of tumours of haematopoietic and lymphoid tissues. 4th edition. International Agency for Research on Cancer (IARC), 2008
Thieblemont C, Coiffier B. Lymphoma in older patients. J Clin Oncol 2007 May 10;25(14):1916-23. [PubMed]

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Lymphomas - Related Resources

Cochrane reviews

Other evidence summaries

Other Internet resources

Literature