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Evidence summaries

Hydroxyurea for Psoriasis

Individual patients with psoriasis may respond to treatment with hydroxyurea. Level of evidence: "C"

According to a systematic review 1 there is some evidence that individual patients may respond to treatment with hydroxyurea, based on the one eligible RCT, which was not obtained by the authors' standard search strategy.

Comment: The quality of evidence is downgraded by sparse data and limitations in review methodology.

    References

    • Griffiths CEM, Clark CM, Chalmers RJG,Li Wan Po A, Williams HC.A systematic review of treatments for severe psoriasis. Health Technol Assess 2000;4(40).

Primary/Secondary Keywords