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Evidence summaries

Characteristics of Exertion-Related Acute Myocardial Infarction (MI)

Exertion-related MIs may occur in habitually inactive people with multiple cardiac risk factors. Level of evidence: "C"

According to a prospective observational cohort study 1 on 1 048 patients, those who (n=640) experienced exertion-related MI, were more frequently men (86% vs 68%), hyperlipidaemic (62% vs 40%), smokers (59% vs 37%), morele likely to present with ventricular fibrillation (20% vs 11%), Killip classification III or IV heart failure (44% vs 22%), single-vessel disease (50% vs 28%), and a large thrombus in the infarct artery (64% vs 35%), and were more likely to be classified as having very low or low activity (84% vs 66%). The RR of experiencing an MI during exertion was 10.1 greater than the risk at other times, with the highest risk among patients classified as very low active (RR 30.5, 95% CI 4.4 to 209.9) and low active (RR 20.9, 95% CI 3.1 to 142.1).

    References

    • Giri S, Thompson PD, Kiernan FJ, Clive J, Fram DB, Mitchel JF, Hirst JA, McKay RG, Waters DD. Clinical and angiographic characteristics of exertion-related acute myocardial infarction. JAMA 1999 Nov 10;282(18):1731-6. [PubMed]

Primary/Secondary Keywords