Antihypertensive Therapy in Patients Having Already Suffered from Stroke
Blood pressure lowering drug therapy reduces the risk of stroke reoccurrence in stroke survivors. Level of evidence: "A"A systematic review 1 including 9 studies with a total of 6752 subjects was abstracted in DARE. Treatment reduces risk of stroke in relative terms by 29% (95% CI 5% to 47%). The overall relative risk for total mortality was 0.86 (95% CI 0.73 to 1.02), for cardiovascular mortality 0.77 (95% CI 0.63 to 0.95), for all strokes 0.72 (95% CI 0.61 to 0.85).
References
- Gueyffier F, Boissel JP, Boutitie F, Pocock S, Coope J, Cutler J, Ekbom T, Fagard R, Friedman L, Kerlikowske K, Perry M, Prineas R, Schron E. Effect of antihypertensive treatment in patients having already suffered from stroke. Gathering the evidence. The INDANA (INdividual Data ANalysis of Antihypertensive intervention trials) Project Collaborators. Stroke 1997 Dec;28(12):2557-62. [PubMed] [DARE]