Treatment of Drug Addicts - Related Resources

Cochrane reviews

Evidence is insufficient for conclusions about the effectiveness of naltrexone maintenance treatment in opioid dependence Naltrexone Maintenance Treatment for Opioid Dependence.
There is insufficient evidence to evaluate the effectiveness of sustained-release naltrexone for treatment of opioid dependence Sustained-Release Naltrexone For Opioid Dependence.
Methadone, buprenorphine and oral slow morphine seem to have similar effect for opiate dependence in pregnant women for mother and child outcomes, although the evidence is limited Maintenance Agonist Treatments for Opiate Dependent Pregnant Women.
Therapeutic communities may not provide any significant benefits in comparison with other residential treatment for substance dependents. In prison setting, a therapeutic community may be effective in preventing re-offending post-release Therapeutic Communities for Substance Related Disorder.
Evidence is insufficient for conclusion about the effectiveness of psychosocial treatments used alone in the treatment of people with opiate abuse and dependence Psychosocial Treatment for Opiate Abuse and Dependence.
Buprenorphine is more effective than clonidine or lofexidine and of similar effectiveness to methadone for the management of opioid withdrawal Buprenorfine for the Management of Opioid Withdrawal.
There is insufficient evidence on the detoxification treatments among opiate dependent adolescents Detoxification Treatments for Opiate Dependent Adolescents.
Anticonvulsants may not be more effective than placebo for cocaine dependence Anticonvulsants for Cocaine Dependence.
Antidepressants might possibly be effective for depression during opioid antagonist treatment in opioid dependent patients .
The use of antidepressants for cocaine abuse appears not to be beneficial .
Dopamine antagonists appear not to be effective for cocaine dependence Dopamine Agonists for Cocaine Dependence.
Antidepressant or psychostimulant medications as a replacement therapy may not be effective for amphetamine dependence and withdrawal compared to placeboTreatments for Amphetamine Dependence and Abuse.
Educating young people may have only a very modest effect on drug using behaviour. Motivational interviewing and some family interventions may have some benefit Educating Young People About Drugs.
Adding any psychosocial support to standard pharmacological maintenance treatment do not improve the non-use of heroin during treatment Combining Psychosocial and Agonist Maintenance Treatments for Opioid Dependence.
Psychosocial treatments added to pharmacological opioid detoxification treatments appear to be effective in terms of completion of treatment, results at follow-up and compliance .
Oral substitution treatment for injecting opioid users may reduce drug-related but not sex-related behaviours with a high risk of HIV transmission Substitution Treatment of Injecting Opioid Users for Prevention of HIV Infection.
Clonidin and lofexidine may have similar efficacy than reducing doses of methadone in the management of withdrawal from heroin or methadone. Combinining adrenergic agonists (naltrexone, naloxone) to the regime can reduce withdrawal symptoms, resulting in more intense early withdrawal but less overall severity Adrenergic Agonists Alone and in Combination with Opioid Antagonists for the Management of Opioid Withdrawal.
Contracts may have some potential in improving adherence to treatment, prevention and health promotion activities Contracts Between Patients and Healthcare Practitioners for Improving Patients' Adherence.
Antipsychotic medications are probably not effective in reducing cocaine dependence Antipsychotic Medications for Cocaine Dependence.
Psychosocial interventions may have some benefit on reducing dropout from treatment and drug consumption for cocaine and psychostimulant amphetamines related disorders .
The evidence is insufficient to support any one psychosocial treatment over another to reduce substance use (or improve mental state) by people with serious mental illnesses Psychosocial Interventions for People with Both Severe Mental Illness and Substance Misuse.
Both haloperidol and olanzapine appear to be effective in the treatment of amphetamine psychosis Treatment for Amphetamine Psychosis.

Other evidence summaries

Family-couples therapy is superior to non-family modalities in the treatment of drug abuse .

Literature

Kakko J, Svanborg KD, Kreek MJ, Heilig M. 1-year retention and social function after buprenorphine-assisted relapse prevention treatment for heroin dependence in Sweden: a randomised, placebo-controlled trial. Lancet 2003 Feb 22;361(9358):662-8. [PubMed]

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References

Treatment of Drug Addicts - Related Resources

Cochrane reviews

Other evidence summaries

Literature