Disease/condition | Description | Further information |
---|---|---|
Acrocyanosis | Hereditary and often congenital condition Peripheral body parts are evenly bluish and there are no tricolour changes. | New onset in an adult may be associated with an autoimmune disease or anorexia nervosa, for example. |
Chilblains 1 | As a result of prolonged cold exposure, purplish spots appear on the skin or a firm swelling can be felt in the skin. | The lesions often heal slowly. |
Cold urticaria Hives (Urticaria) | A typical, itchy urticarial rash appears after cold exposure. | Antihistamines can be used to treat itching. Most importantly, the skin must be protected from cold. |
Erythromelalgia | Heat, severe erythema and burning, most commonly affecting the feet. | |
Livedo reticularis, or a net-like pattern on the skin | Net-like pattern on the skin The pattern is non-blanchable. | Occurs in association with conditions such as systemic autoimmune diseases. Symptoms of acute onset, in particular, always require medical assessment. |
Erythrocyanosis | A benign, typical colour change occurring on the legs of young or middle-aged women in association with cold exposure and subsiding with age | This is due to slowing of the circulation in the skin and the subcutaneous fatty tissue. |
Type of disease or condition | Aetiology |
---|---|
Systemic connective tissue disorder | Scleroderma Systemic Sclerosis (in 90%)
|
Systemic lupus erythematosus (SLE) Systemic Lupus Erythematosus (Sle) (in 40%)
| |
Rheumatoid arthritis Rheumatoid Arthritis (in 10%) | |
Dermatomyositis and polymyositis Myositis (in 25%) | |
Mixed connective tissue disease (MCTD) Mixed Connective Tissue Disease (Mctd) (in 85%) | |
Eating disorder | Anoreksia nervosa |
Obstructive vascular disease | Atherosclerosis |
Buerger's disease | |
Takayasu arteritis Vasculitides | |
Aneurysm of the subclavian artery | |
Thoracic outlet syndrome Thoracic Outlet Syndrome | |
Exposure to external factors | Work where an individual is subjected to vibration or shaking (may be compensated as an oocupational disease) Hand-Arm Vibration Syndrome (Vibration-Induced White Fingers) |
Exposure to vinyl chloride, mercury or cold | |
Other diseases | Severe mental trauma |
Lyme disease Lyme Borreliosis (LB) | |
Hypothyroidism Hypothyroidism | |
Cryoglobulinaemia Vasculitides | |
Malignant disease | |
Chronic fatigue syndrome | |
Complex regional pain syndrome (CRPS) Complex Regional Pain Syndrome (Crps) | |
Carpal tunnel syndrome Carpal Tunnel Syndrome (CTS) | |
Magnesium deficiency Magnesium Deficiency | |
MS Multiple Sclerosis (Ms) | |
Erythromelalgia | |
Idiopathic PAH Increased Pulmonary Blood Pressure: Pulmonary Arterial Hypertension and Chronic Thromboembolic Pulmonary Hypertension (10-14% have RP) | |
Cholesterol embolization Cholesterol Embolization | |
Endocarditis Infective Endocarditis | |
Polycythaemia vera Polycythaemia Vera (Pv) | |
Hyperviscosity syndrome | |
Myxoma | |
Drug-induced RP | Beta blockers |
Sulfasalazine | |
Ciclosporin | |
Sympathomimetics | |
Ergotamine derivatives | |
Cocaine | |
Hormonal contraceptives |
Disease | Typical symptoms |
---|---|
SLE Systemic Lupus Erythematosus (Sle) | Butterfly rash |
Photosensitivity | |
Arthritis or joint and muscle pain | |
Nephritis, pleuritis or pericarditis | |
Prolonged fever | |
Systemic sclerosis Systemic Sclerosis | Swelling of the fingers (sausage fingers) |
The skin later becoming thicker, shiny and stiff and being attached to the underlying tissue | |
Stiffening and loss of range of motion of joints; for example, being unable to clench the fist | |
Distension of and bleedings from nailfold capillaries | |
Mask-like facial appearance and puckered lips | |
Cutaneous telangiectasia | |
Dysphagia, impaired motility and strictures of the oesophagus | |
Dyspnoea and lung fibrosis on chest radiograph | |
Arthritis | |
Polymyositis and dermatomyositis Myositis | Proximal muscle weakness |
Acute dysphagia | |
Purplish rash on the eyelids, neck and chest | |
Purplish, scaly, patchy rash on the extensor surfaces of the limbs | |
Prolonged fever | |
Arthritis | |
MCTD syndrome Mixed Connective Tissue Disease (Mctd) | May be quite varied with features of conditions such as systemic sclerosis, polymyositis or rheumatoid arthritis. |
Severe sausage-like swelling of the fingers is particularly typical. |