A Cochrane review [Abstract] 1 included 21 studies with a total of 1087 subjects. Eight trials compared a neurophysiological approach with another approach; eight compared a motor learning approach with another approach; and eight compared a mixed approach with another approach. A mixed approach was significantly more effective than no treatment or placebo control for improving functional independence (standardised mean difference [SMD] 0.94, 95% CI 0.08 to 1.80; 5 trials, n=427). There was no significant evidence that any single approach had a better outcome than any other single approach or no treatment control.
Comment: The quality of evidence is downgraded by limitations in study quality and by inconsistency (heterogeneity in interventions and outcomes).
Primary/Secondary Keywords