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Evidence summaries

Parapharyngeal and Retropharyngeal Abscesses - Etiology and Treatment

Deep space neck infections in children may often be successfully managed with medical therapy alone, especially if they are over 4 years old. Level of evidence: "C"

In a retrospective review of 185 patients with deep neck infections 1 in the Taiwan University Hospital between 1997 and 2002, the parapharyngeal space was the most commonly involved space (39%). Odontogenic infections (53%) and upper airway infections (31%) were the two most common identified causes. Streptococcus viridans and Klebsiella pneumoniae were the most common organisms (34% each). Of the 142 patients with abscess, 103 patients (72.5%) underwent surgical drainages.

For a consecutive case series 2 a total of 178 children were included. They were treated for retropharyngeal or parapharyngeal infections.Median age was 34.5 months (2.9 years; range, 2-142 months); two-thirds were male. Increased surgical drainage was found in children age HASH(0x2f830d0) 15 months (p =0 .002) and for abscesses >2.2 cm (p = 0.0001). Risk factors associated with increased likelihood of medical therapy failure included age HASH(0x2f830d0) 51 months, intensive care unit admission, and CT findings consistent with abscess size >2.2 cm. Methicillin-resistant Staphylococcus aureus infections were found more often in younger children, with the highest incidence in those HASH(0x2f830d0) 15 months of age (p = 0.001). All children had resolution of infection.

A third retrospective chart review 3 included 54 children up to 15 years with a CT-confirmed diagnosis of retropharyngeal or parapharyngeal abscess. Antibiotic treatment alone was compared with antibiotics plus abscess drainage. Younger children within the group with smaller abscesses were more likely to need surgical drainage (p<0.05). Of 13 children requiring operative management, 10 underwent a period of antibiotic treatment and observation prior to surgery, 8 (80%) had fever beyond 48 h compared with 3 (23%) in the non-surgical group (p<0.01). A total of 27 children had an abscess > 25 mm diameter on CT scan, four (15%) of whom responded quickly to antibiotics and were managed non-operatively, while the rest underwent surgery.

References

  • Huang TT, Liu TC, Chen PR, Tseng FY, Yeh TH, Chen YS. Deep neck infection: analysis of 185 cases. Head Neck 2004 Oct;26(10):854-60. [PubMed]
  • Cheng J, Elden L. Children with deep space neck infections: our experience with 178 children. Otolaryngol Head Neck Surg 2013;148(6):1037-42. [PubMed]
  • Wong DK, Brown C, Mills N et al. To drain or not to drain - management of pediatric deep neck abscesses: a case-control study. Int J Pediatr Otorhinolaryngol 2012;76(12):1810-3. [PubMed]

Primary/Secondary Keywords