Even one of the following: | At least two of the following: |
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Chronic hypertension | Primigravida |
SLE or positive antiphospholipid antibodies | Age > 40 yrs |
Chronic renal disease | BMI > 30 kg/m2 |
Type 1 or 2 diabetes | Mother's or sister's pre-eclampsia |
Previously: | Pregnancy achieved with donated eggs |
Pre-eclampsia | >10 yrs between pregnancies |
Placental insufficiency with foetal growth disturbance | Multiple pregnancy |
Foetal intrauterine death associated with placental causes | Pregnancy-associated plasma protein A MoM < 0.4 in the first trimester screening |