A systematic review 1 including 19 studies (10 of headache, n=550; 3 of diabetic neuropathy, n=83; 3 of fibromyalgia, n=83; 3 of mixed chronic pain, n=119) was abstracted in DARE. The results were inconsistent in all studies with the exception of mixed chronic pain where SSRIs were more effective than placebo.
Comment: The quality of evidence is downgraded by sparse data and inconsistency.
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