A Cochrane review [Abstract] 1 included 28 studies with a total of 39 776 study subjects. The studies indicated that case management strategies and higher hospital and ward volume of HIV-positive patients were associated with decreased mortality. Case management was also associated with increased receipt of antiretrovirals. The results for multidisciplinary teams or multi-faceted treatment varied. None of the studies examined quality of life or immunological or virological outcomes. Healthcare utilization outcomes were mixed.
Comment: The quality of evidence is downgraded by limitations in study quality and by inconsistency (heterogeneity in interventions and outcomes).
Primary/Secondary Keywords