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Evidence summaries

Nsaids in Acute Renal Colic

Non-steroidal anti-inflammatory agents are more effective than placebo and at least as effective than narcotic analgesics for acute renal colic. Level of evidence: "A"

A systematic review 1 including 20 studies with a total of about 880 subjects was abstracted in DARE. The outcome was relief of pain within 20 - 30 minutes. The drugs evaluated were intramuscular diclofenac or intravenous indomethacin and analgesic agents (mainly narcotic agents).

NSAIDs were more effective than placebo (RR = 2.34, 95% CI 1.79 to3.07) and as effective or slightly better than analgesic agents (partial pain relief, RR = 1.07, 95% CI 1.02 to 1.12; complete pain relief, RR = 1.19, 95% CI 1.03 to 1.37).

References

Primary/Secondary Keywords